pea1 ecacc Search Results


pea1 ecacc  (CancerTools Org)
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CancerTools Org pea1 ecacc
A Wound healing assay for the <t>PEA1/PEA2</t> ( N = 3 independent replicates), OVCAR3 ( N = 4), OVCAR4 ( N = 4), and PEO1/4 ( N = 3) isogenic cell line pairs. Error bars represent standard deviation. * indicates p -value < 0.05 in paired t-tests and ns indicates non-significant p -value > 0.05. B Representative ALDH1A1 western blot images of all isogenic cell line pairs along with platinum resistant cell lines JHOS2 and COV362. GAPDH serves as a loading control. C CD133 and ALDH1A1 western blot images of all isogenic cell line pairs with or without cisplatin treatment at each respective cell line’s IC 50 for 72 hours. GAPDH serves as a loading control. D Volcano plot showing differential expression between isogenic platinum-resistant cell lines, comparing resistant to their sensitive counterpart. Points are color-coded based on the specific pair, and statistically significant ( | log2 fold change |>1.5, adjusted p -value < 0.05) genes are labeled by gene name.
Pea1 Ecacc, supplied by CancerTools Org, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/pea1+ecacc/PEA1/pmc12396967-54-0-5
Average 93 stars, based on 1 article reviews
pea1 ecacc - by Bioz Stars, 2026-09
93/100 stars
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A Wound healing assay for the PEA1/PEA2 ( N = 3 independent replicates), OVCAR3 ( N = 4), OVCAR4 ( N = 4), and PEO1/4 ( N = 3) isogenic cell line pairs. Error bars represent standard deviation. * indicates p -value < 0.05 in paired t-tests and ns indicates non-significant p -value > 0.05. B Representative ALDH1A1 western blot images of all isogenic cell line pairs along with platinum resistant cell lines JHOS2 and COV362. GAPDH serves as a loading control. C CD133 and ALDH1A1 western blot images of all isogenic cell line pairs with or without cisplatin treatment at each respective cell line’s IC 50 for 72 hours. GAPDH serves as a loading control. D Volcano plot showing differential expression between isogenic platinum-resistant cell lines, comparing resistant to their sensitive counterpart. Points are color-coded based on the specific pair, and statistically significant ( | log2 fold change |>1.5, adjusted p -value < 0.05) genes are labeled by gene name.

Journal: Cancer Gene Therapy

Article Title: Cell-intrinsic platinum response and associated genetic and gene expression signatures in ovarian cancer

doi: 10.1038/s41417-025-00941-5

Figure Lengend Snippet: A Wound healing assay for the PEA1/PEA2 ( N = 3 independent replicates), OVCAR3 ( N = 4), OVCAR4 ( N = 4), and PEO1/4 ( N = 3) isogenic cell line pairs. Error bars represent standard deviation. * indicates p -value < 0.05 in paired t-tests and ns indicates non-significant p -value > 0.05. B Representative ALDH1A1 western blot images of all isogenic cell line pairs along with platinum resistant cell lines JHOS2 and COV362. GAPDH serves as a loading control. C CD133 and ALDH1A1 western blot images of all isogenic cell line pairs with or without cisplatin treatment at each respective cell line’s IC 50 for 72 hours. GAPDH serves as a loading control. D Volcano plot showing differential expression between isogenic platinum-resistant cell lines, comparing resistant to their sensitive counterpart. Points are color-coded based on the specific pair, and statistically significant ( | log2 fold change |>1.5, adjusted p -value < 0.05) genes are labeled by gene name.

Article Snippet: PEA1 (ECACC), PEA2 (ECACC), PEO1 (CancerTools.org), PEO4 (ECACC), PEO6 (ECACC) were cultured in RPMI 1640 with 10% FBS and 1 mM NaP.

Techniques: Wound Healing Assay, Standard Deviation, Western Blot, Control, Quantitative Proteomics, Labeling